Successful Management of Hydroxyurea-induced Leg Ulcers in Essential Thrombocythemia: Report of 3 Cases

Successful Management of Hydroxyurea-induced Leg Ulcers in Essential Thrombocythemia: Report of 3 Cases

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Essential thrombocythemia is one of the myeloproliferative neoplasms nightstick twm-850xl with a plethora of thrombohemorrhagic complications.Hydroxyurea has been proven to be an effective treatment for this condition.However, it is not without side effects.We herein report 3 patients with essential thrombocythemia treated with hydroxyurea who developed refractory leg ulcers, and we outline their successful management.

We also review the literature to shed light on 3 nef runes the mechanism of this toxicity.Awareness of this important treatment complication is important to avoid the pitfall of futile invasive interventions.